T2-GI * IBS(irritable bowel syndrome) formula

New form of irritable bowel syndrome discovered

September 12, 2013

The new condition occurs after an acute bout of diverticulitis, scientists at the University of California, Los Angeles have found.

As they age, most people develop diverticulosis, or pouches in the lining of the colon. The pouches usually don`t cause any problems but occasionally, they become inflamed, leading to diverticulitis, which causes pain and infection in the abdomen.

The condition, called Post-Diverticulitis Irritable Bowel Syndrome (PDV-IBS), validates the irritable bowel symptoms that many patients report long after suffering a bout of diverticulitis, but that many physicians wave off as being part of the original condition.

"We`ve known for a long time that after some people develop diverticulitis, they`re a different person. They experience recurrent abdominal pains, cramping and diarrhea that they didn`t have before," said study senior author Dr Brennan Spiegel, an associate professor of medicine at the David Geffen School of Medicine at UCLA.

"The prevailing wisdom has been that once diverticulitis is treated, it`s gone. But we`ve shown that IBS symptoms occur after the diverticulitis, and it may result from an inflammatory process like a bomb going off in the body and leaving residual damage," he said.

"A major surprise in our study was that diverticulitis patients not only developed IBS at a higher rate than the controls, but they also developed mood disorders like depression and anxiety at a higher rate," Spiegel said.

"Because IBS and mood disorders often go hand in hand, this suggests that acute diverticulitis might even set off a process leading to long-standing changes in the brain-gut axis," he said.

The discovery of PDV-IBS could mean better attention to patients complaining of symptoms after diverticulitis, symptoms that up until now may have been dismissed by physicians.

Spiegel said the PDV-IBS patients often report ongoing IBS symptoms after the diverticulitis has long passed, and this study supports their beliefs and introduces a new diagnosis.

More than 1,000 patient records from the West Los Angeles Veteran`s Affairs Medical Centre were examined for the two-year study, including patients that had suffered acute diverticulitis and another group of patients that did not have it.

September 07, 2013, 14:52,


April Is IBS Awareness Month

April 24, 2013

Since 1997, the International Foundation for Functional Gastrointestinal Disorders (IFFGD) has been recognizing April as IBS Awareness Month.

Earlier this month, the organization cosponsored the 10th International Symposium on Functional Gastrointestinal Disorders, held in Milwaukee, April 12-14. The biennial conference, which IFFGD says has been described as “an educational jewel,” attracts scientists and health care professionals from around the world. International experts in irritable ...

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AstraZeneca, Ironwood will bring irritable bowel syndrome treatment to China

March 14, 2013

AstraZeneca and Ironwood are jointly responsible for strategic oversight of the development and commercialization of linaclotide in China. AstraZeneca will have primary responsibility for the local operational execution.
Under the terms of the collaboration, AstraZeneca will make an upfront payment of $25 million to Ironwood and will share the net profits and losses associated with linaclotide in China, with AstraZeneca carrying 55 percent of each until a certain specified milestone is achieve...

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Studying The Causes Of Irritable Bowel Syndrome - GENIEUR

March 11, 2013
Experts and scientists from 19 European countries are getting together to investigate the causes of IBS (irritable bowel syndrome) with the aim of better understanding the condition and improving diagnosis and treatment.

The team is led by researchers from the Sahlgrenska Academy, University of Gothenburg and Karolinska Institutet, both in Sweden. They have set up the Europe-wide network GENIEUR - an interdisciplinary network for researching into the causes of IBS.

GENIEUR, which stands for Gen...

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Possible Overlap Of IBS Symptoms And Inflammatory Bowel Disease

March 10, 2013
Research unveiled at the American College of Gastroenterology's (ACG) 77th Annual Scientific meeting in Las Vegas suggests a possible overlap of symptoms of two prevalent GI disorders: irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD) and further suggests a possible link between subtle GI tract inflammation and IBS symptoms - a link that is also the focus of the first systemic review of the literature on this topic and an editorial both published in this month's American Jou...

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In 2008, $141 million was spent for the treatment of Crohn's disease in Canada

November 2, 2012
There are some statistics for your understanding of Crohn's Disease in Canada.
-In 2008, $141 million was spent on prescription drugs for the treatment of Crohn's disease.
-The majority of Crohn's disease patients will require hospitalization at some point and more than half will require surgery.
-Worldwide, there are 177 pharmaceutical products indicated for Crohn's disease and 52 pharmaceutical products in clinical trials.
-Most patients develop Crohn's disease during their 20s
-Patients with m...

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5 million Canadians suffer from IBS

October 31, 2012
IBS(Irritable Bowel Syndrome)

Irritable Bowel Syndrome or IBS is a common chronic gastrointestinal disorder. Those affected may experience abdominal pain, bloating and an irregular bowel pattern alternating between constipation and diarrhea. People with IBS may also have associated upper abdominal symptoms such as heartburn, nausea, bloating and abdominal pain.

-Canada has one of the highest rates of IBS in the world.
-5 million Canadians suffer from IBS with 120,000 Canadians developing IBS eac...

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